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Living With Hemochromatosis
11/03/10
I found a comment today from someone who suffers from hemochromatosis (toxic iron overload) who said a chemist friend recommended eating cabbage. He said the results were so drastic in reducing his iron load that his doctor retested him …got no idea if this is true but wtf…cabbage is good for ya.
PS. Are you drinking plenty of water
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Hereditary Hemochromatosis (HH) is the most common genetic disorderof persons of northern European extraction. Approximately 1 in 200 to 300 persons of northern European extraction has the disorder.
Hemochromatosis has beenfound in virtually all populations. There are different forms of the disorder but here we will consider northern Europeans.
The incidence of HH in persons of Irish extraction is higher than the average rate for northern Europeans. A rate exceeding 1 in 100 has been found in Ireland. Most cases of HH occur in patients who have two copies of the mutation known as C282Y which is found on the HFE gene.
A smaller percentage of patients may carry one copy of C282Y and one copy of another mutation known as H63D. These patients are known as compound heterozygotes. Other less common combinations occur such as C282Y heterozygotes where the patient only has one copy of C282Y but has hemochromatosis.
In these cases another gene or genes is present. Sometimes this gene or genes can be identified. Identification of such genes is currently the source of
much research into hemochromatosis.
HH is characterized by excessive absorption of dietary iron and a consequent progressive increase in total body iron stores. Of interest it is non-heme iron or the iron contained in sources such as vegetables which is excessively absorbed in HH. Iron accumulates in the parenchymal cells of the liver, the heart, pancreas, anterior pituitary and skin.
This accumulation of iron in body tissues causes disease. The body needs iron to function and has an ability to store large amounts especially in the liver. However when this storage capacity is exceeded disease occurs.
In severe HH the disorder manifests as potentially life threatening conditions such as septicemia, cirrhosis of the liver, liver cancer, diabetes, heart failure and heart arrhythmias.
Arthritis is common and a severe arthritis involving numerous joints may occur. Ovarian and testicular failure secondary to iron deposition in the anterior pituitary and possibly the hypothalamus may occur.
Rarely hypothyroidism may occur.
If HH is not treated liver disease may be fatal. The morbidity and mortality of HH can be reduced by early diagnosis and treatment by phlebotomy or blood letting. If a patient with HH is treated before cirrhosis of the liver develops liver functioning can be improved
and fibrosis of the liver may be reversed.
There is frequently a delay between the onset of symptoms and diagnosis. This is because early symptoms such as fatigue and arthralgia are nonspecific. A high degree of suspicion is needed to make the diagnosis of HH in a patient if the initial symptoms are vague. Because of the inherited nature of hemochromatosis relatives
of those with HH are at increased risk.
Here it is easier to make the diagnosis because an initial case
has been identified. It is very important to make an early
diagnosis of Hereditary Hemochromatosis because patients who have
not developed cirrhosis and are treated by phlebotomy have a normal
life expectancy. Treatment is life long.
If you Suffer from Hemochromatosis, have a Relative with the
disease or Just wish for more information You must Purchase
“Ironic Health”.
An insightful look at how hemochromatosis affects so many different
people. Very readable and interesting. Is a ‘must read’ for both
patients and their doctors. Make it a point to read this one from
cover to cover. Just click the below link
http://www.ironoverload.info/ironichealth
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Hemochromatosis Symptoms
Probably the greatest difficulty in diagnosing early
hemochromatosis is that it is nonspecific and symptoms are vague.
Many sufferers are often diagnosed with the “flu” or “chronic
fatigue syndrome”. Some have suffered years where they have been
suspected of malingering. Paradoxically anemia may firstly be
suspected because of decreased energy.
If the correct tests are not done sufferers may even be given iron
tablets which further worsen their symptoms. Iron overload is
insidious and usually takes many years to develop. Women may begin
to load iron at menopause as the phlebotomy effect of menstruation
has ceased. If this possibility is not suspected the symptoms may
be written off as being due to “hormonal changes”.
The earliest symptoms of hemochromatosis are fatigue and arthralgia
or aching joints. Once iron has begun to accumulate in body tissues
the liver may be affected. In the past it has not been uncommon for
sufferers to be suspected or being secret drinkers when abnormal
liver function tests are found.
As iron continues to accumulate the condition of the liver may
worsen and other organs may be affected.
Other organs which may be involved include the skin, pancreas,
ovaries, testes, heart, digestive system, thyroid and joints.
Annoying skin rashes, palpitations, impotence and diabetes may be a
consequence of too much iron. Many patients suffer from recurrent
infections and may decide to take “immune boosters” which are
metabolized by the liver. This can make their condition worse.
Patients with severe hemochromatosis may present with septicemia or
blood poisoning, heart failure, failure of the reproductive organs
and severe arthritis where joint replacement is necessary. In the
worst cases liver transplant may be necessary. Those cases that
require liver transplant have a 50% mortality within the year after
transplant.
This mortality is often due to heart problems or septicemia. Men
over 55 years of age with severe hemochromatosis have 200 times the
chance of developing liver cancer.
It is important to have a high index of suspicion for the
possibility of hemochromatosis as the disorder is a great mimicker
of other disorders. With the rapidly advancing knowledge on the
disorder it is becoming more common for doctors to order
transferrin (transferrin-iron) saturations (TS) on their patients
and unsuspected cases of hemochromatosis are being found more
frequently.
Elevation of TS values is a big clue as to the diagnosis. However
if only ferritin levels are ordered an early case of
hemochromatosis or even a person with hemochromatosis who has been
a blood donor may be missed. Testing for iron studies is not
expensive. Taken together the TS value and ferritin level will
detect most cases of hemochromatosis.
It is important to diagnose hemochromatosis early as it can be
treated easily. Fortunately with increased awareness this is now
happening. While the patient with end stage hemochromatosis may
save the lives of others as he (usually but sometimes she) has
alerted the doctor and relatives that others may have
hemochromatosis, this represents an unnecessary tragedy that
fortunately is becoming rarer.
People with a specific type of hemochromatosis, an inherited disorder that causes the body to absorb and store too much iron, have more than twice the risk of stroke, according to a report published in Neurology.
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Yes, I know that the subject line sounds like one of those bait and switch techniques, where you throw out an idea that sounds too good to be true and then you sell an idea that doesn’t match up with the promise.

But not this time. I just found a book called Hot Metabolism that explains how you really can lose weight without giving away the calories
I’m doing this because I quit smoking finally and packed on 15 pounds in less than 90 days. Yeow!
Basically, the trick involves gaining control over your metabolism, so that you can burn more calories every day than you consume. Naturally, if you can do that, you will experience weight loss.
Read more about this hot technique here
Water. It’s That Clear Stuff
16/08/09
Hey I thought I’d just remind everybody, HH or not…
Your body is estimated to be about 60 to 70 percent water. Blood is mostly water, and your muscles, lungs, and brain all contain a lot of water. Your body needs water to regulate body temperature and to provide the means for nutrients to travel to all your organs. Water also transports oxygen to your cells, removes waste, and protects your joints and organs.
So…drink tons. When I was really powering the water, I was dumpin pounds like mad. But since I quit smokin……
I gained 15 pounds in 90 days. So I will be starting to power the H20 again. Try it. You’ll feel good.
I’ve heard that we need an ounce of water for every 2 pounds of your weight. That would be 69 OZs for me.
138 pounds.
The Hemochromatosis Cookbook
12/08/09
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Book Description
Hemochromatosis is one of modern medicine's greatest oversights.
An inherited metabolic iron disorder, it is most common in people
of northern European descent and most prominent among Scotch-Irish.
For people with metabolic iron disorders, controlling one's intake
of iron contributes to wellness and the prevention of such chronic
diseases as heart disease, diabetes, arthritis, liver disease,
impotence, and depression.
The Hemochromatosis Cookbook is designed specifically for those
who suffer from such iron disorders. It has chapters on appetizers,
salads, fruits and vegetables, main courses (including casseroles),
breads and muffins, and desserts.
Risk factors for primary liver cancer include Having hepatitis, having cirrhosis, or scarring of the liver, being male, Low weight at birth. Persons with associated cirrhosis brought on by chronic hepatitis B or C infections, alcohol, and hemochromatosis have the highest risk of developing this kind of cancer.
Liver cancer is the third leading cause of cancer deaths in the world after lung and stomach cancer
The cause of liver cancer is usually cirrhosis (scarring of the liver). Cirrhosis may be caused by viral hepatitis, primarily hepatitis B and C, alcohol abuse, hemochromatosis, certain auto-immune diseases of the liver, and other diseases that result in chronic inflammation of the liver.
National Hemochromatosis Month
16/06/09
May 2009 was National Hemochromatosis
Genetic Screening & Awareness Month.
Sponsored by the American Hemochromatosis Society
Help us to spread the word about Hereditary Hemochromatosis.
The American Hemochromatosis Society’s, “National
Hemochromatosis Genetic Testing and Awareness Month”
is May 2009 (www.americanhs.org).
The American Hemochromatosis Society (AHS) is urging
Americans to test themselves for hereditary hemochromatosis,
also known as iron overload or iron storage disease.
Hemochromatosis is easy to diagnose. You can even diagnose
it yourself through a self testing lab. And, it is also
easy to treat with bloodletting, identical to blood donation.
In fact, you can prevent hemochromatosis by becoming an
avid community blood donor.
Hemochromatosis And Anemia
26/03/09
When I was first diagnosed with HH,
my doctor bled me a bunch for the first months.
300 CCs twice a week. He made me anemic to get
my body to use up the iron that was stored in
my heart, liver, pancreas, brain, etc.
Then he slowed down the phlebs until I wasn't
anemic anymore. He told me to take folic acid.
Because folic acid is needed for cell replication
and growth, rapidly regenerating cells such as red
blood cells and immune cells have a high need for
it. Folic acid is found in many foods, such as
asparagus, broccoli, endive, spinach. lima beans.
Anemia and associated diseases compromise the
oxygen-transport capabilities of red blood cells
and the normal immune function of both red and
white blood cells due to increased adhesion,
reduction, or malfunction.
Scientific study strongly suggests that trace
minerals may act as an adjunctive preventive
therapy to reduce the effect of anemia on normal
blood cell function.
Aging, viral infections, blood diseases, and a
variety of drugs, as well as cancer chemotherapy
and radiation therapy, can cause deficits in red
blood cells, white blood cells, and blood platelet
production.
I'm no doctor but I would think being anemic is
not a good thing. Having HH already is very hard
on our bodies. We are 32% more likely to suffer
from stroke and heart attack too.
Symptoms of Anemia
Weakness and faintness
Shortness of breath
Increased heart rate
Headaches
Sore tongue
Nausea and loss of appetite
Dizziness
Bleeding gums
Confusion and dementia
Heart failure in some severe cases
